Our Research Strategy:
A Pathway to Transformative Therapies
As a new organization, Reed’s Reach for 15q13.3 is founded on a clear and urgent mission: to accelerate the development of transformative therapies for 15q13.3 variations. We are actively working with scientists and researchers to develop a pipeline of high-impact research initiatives. This page outlines our strategic focus areas, which will be updated with specific projects as they are launched.
Our approach is designed to balance the immediate needs of our community with the ultimate goal of addressing the root genetic causes of the syndrome.
We are building a research portfolio centered on two key areas:
1. Prioritizing Near-Term Impact We are actively exploring opportunities to fund research into therapies that can provide near-term relief for our community. This includes investigating the potential of repurposed compounds with established safety profiles and supporting the development of innovative drug delivery methods to improve the effectiveness of existing treatments.
2. Addressing the Root Genetic Cause Our long-term vision is centered on funding foundational treatments that address the underlying genetics of 15q13.3. This includes pursuing advanced genetic medicines, such as Antisense Oligonucleotides (ASOs) and Gene Therapies, that aim to restore the function of critical genes like CHRNA7 and OTUD7A.
Our Strategic Focus Areas
Our Commitment to Broader Impact
A core tenet of our mission is to explicitly address the broader impact of our research. 15q13.3 variations are a significant genetic risk factor for conditions like epilepsy, bipolar disorder, schizophrenia, and autism spectrum disorder. By funding research into these specific genetic pathways, we believe we can unlock critical insights and potential therapies that will benefit a much larger patient population.
A Call for Collaboration
As we formalize these research initiatives, we are eager to connect with researchers, clinicians, and potential partners. If you are a scientist working in a related field or a representative of a research institution, we encourage you to connect with us to discuss potential collaborations.
With a clear strategy and the support of our community, we can accelerate the journey from scientific discovery to life-changing treatments.
